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Search Results for " cd40 antigen "

1

抑制剂 & 化合物

12

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T77090	Mitazalimab
	Mitazalimab（ADC-1013; JNJ-64457107）是一种FcγR依赖性CD40激动剂，以肿瘤导向活性为特征。该化合物通过激活抗原呈递细胞（如树突状细胞[DC]），启动肿瘤反应性T细胞，进而诱导肿瘤特异性T细胞浸润并杀死肿瘤，有效重塑肿瘤浸润性骨髓微环境。

化合物

Cat.No: T77090

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-00170	CD40 Protein, Human, Recombinant (aa 21-193, His & Avi), Biotinylated CD40 antigen, TNFRSF5,CD	Human	HEK293 Cells
	CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.CD40 molecule is a potential target for cancer immunotherapy. There are number of completed and ongoing clinical trials where agonistic anti-CD40 monoclonal antibodies are employed to activate an anti-tumor T cell response via activation of dendritic cells.
TMPJ-00634	CD40 Protein, Cynomolgus, Recombinant (His) CDw40,TNFRSF5,B-Cell Surface Antigen	Cynomolgus	HEK293 Cells
	CD40 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 28-30 KDa and the accession number is G7PG38.
TMPJ-01420	CD40 Protein, Cynomolgus, Recombinant (hFc) Tumor Necrosis Factor Receptor Superfamily member 5,B-Cell S...	Cynomolgus	HEK293 Cells
	CD40 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 48-70 KDa and the accession number is XP_005569275.1.
TMPJ-00153	CD40 Ligand Protein, Human, Recombinant (His & Flag) CD40LG,Tumor Necrosis Factor Ligand Superf...	Human	HEK293 Cells
	CD40 Ligand Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 19-24 KDa and the accession number is P29965.
TMPJ-00150	CD40 Ligand Protein, Human, Recombinant (Mammalian) CD40LG,Tumor Necrosis Factor Ligand Superf...	Human	HEK293 Cells
	CD40 Ligand Protein, Human, Recombinant (Mammalian) is expressed in HEK293 mammalian cells. The predicted molecular weight is 16-18 KDa and the accession number is P29965.
TMPJ-00151	CD40 Ligand Protein, Human, Recombinant CD40LG,CD40 Ligand,TRAP,...	Human	E. coli
	CD40 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 KDa and the accession number is P29965.
TMPJ-00152	CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated CD40 Ligand,TNF-Related Activation Protein...	Human	HEK293 Cells
	CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-6xHis-Avi tag. The predicted molecular weight is 23-28 KDa and the accession number is P29965.
TMPK-01398	CD40 Ligand Trimer Protein, Human, Recombinant (hFc) CD40 Ligand,CD40LIGM,IGM...	Human	HEK293 Cells
	CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells.
TMPK-00154	CD40 Ligand Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated IMD3,TNFSF5IMD3,TRAP,CD40LIGM,CD<...	Human	HEK293 Cells
	CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells. CD40 Ligand Prote...
TMPK-00860	CD40 Ligand Protein, Mouse, Recombinant (monomeric hFc) IMD3,CD40LG,CD40L,IGM,TR...	Mouse	HEK293 Cells
	CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells. CD40 Ligand Prote...
TMPJ-00920	CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His) TNFSF5,Tumor necrosis factor ligand superfamily member 5,	Mouse	HEK293 Cells
	CD40 Ligand, also known as TNFSF5, CD154, is a type II transmembrane glycoprotein member of the TNF superfamily. Mature mouse CD40 Ligand consists of a 22 amino acid (aa) cytoplasmic domain, a transmembrane segment, and a 214 aa extracellular region. CD40 Ligand is expressed as a homotrimer on platelets and activated T cells and B cells. It is upregulated following stimulation of basophils, eosinophils, fibroblasts, mast cells, monocytes, natural killer cells, vascular endothelial cells, and sm...
TMPJ-00226	SLAMF1 Protein, Mouse, Recombinant (His) signaling lymphocytic activation molecule,SLAM family member...	Mouse	HEK293 Cells
	Signaling lymphocyte activation molecule (SLAM), is a self-ligand glycoprotein which exists not only found on the surface of activated and memory T cells, but also on the surface of activated B cells, dendritic cells, and macrophages. SLAM consists of a extracellular domain (ECD) with two Ig-like domains,transmembrane segment, and cytoplasmic domain with three immunoreceptor tyrosine switch motifs (ITSM). SLAM is thought to play an important role in adhesion between T cells and APCs and has been...

重组蛋白

CD40 Protein, Human, Recombinant (aa 21-193, His & Avi), Biotinylated

Cat.No: TMPK-00170

Species: Human

Expression System: HEK293 Cells

CD40 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPJ-00634

Species: Cynomolgus

Expression System: HEK293 Cells

CD40 Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPJ-01420

Species: Cynomolgus

Expression System: HEK293 Cells

CD40 Ligand Protein, Human, Recombinant (His & Flag)

Cat.No: TMPJ-00153

Species: Human

Expression System: HEK293 Cells

CD40 Ligand Protein, Human, Recombinant (Mammalian)

Cat.No: TMPJ-00150

Species: Human

Expression System: HEK293 Cells

CD40 Ligand Protein, Human, Recombinant

Cat.No: TMPJ-00151

Species: Human

Expression System: E. coli

CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00152

Species: Human

Expression System: HEK293 Cells

CD40 Ligand Trimer Protein, Human, Recombinant (hFc)

Cat.No: TMPK-01398

Species: Human

Expression System: HEK293 Cells

CD40 Ligand Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated

Cat.No: TMPK-00154

Species: Human

Expression System: HEK293 Cells

CD40 Ligand Protein, Mouse, Recombinant (monomeric hFc)

Cat.No: TMPK-00860

Species: Mouse

Expression System: HEK293 Cells

CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His)

Cat.No: TMPJ-00920

Species: Mouse

Expression System: HEK293 Cells

SLAMF1 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00226

Species: Mouse

Expression System: HEK293 Cells

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